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. 2013 Feb 20;8(2):e56131. doi: 10.1371/journal.pone.0056131

Table 2. Results of clinical laboratory tests and placental pathology for preterm birth cases.

Variables Group 1 Group 2 Group 3 Group 4 P value
Culture-positive EONS (n = 6) Presumed EONS & Yes IAI (n = 16) Presumed EONS & No IAI (n = 7) No EONS & No IAI (n = 7)
Amniotic fluid
Glucose ≤15 mg/dLLDH activity ≥419 IU/LWBC count ≥30 cells/µLPositive Gram stain Positive cultures 3 (50)4 (67)4 (67)4 (67)5 (83) 16 (100)16 (100)16 (100)13 (81)16 (100) 4 (57)2 (29)2 (29)0 (0)0 (0) 0 (0)0 (0)0 (0)0 (0)0 (0) <0.001<0.001<0.001<0.001<0.001
Placental pathology
HCA, stages II or III Funisitis, grades 1–4 6 (100)3 (50) 15 (94)11 (69) 5 (71)4 (57) 1 (14)0 (0) <0.001<0.001
Neonatal hematology
ANC, cells/mL *ABC, cells/mL *I:T ratio, % *Platelets, cells/mLx1,000 * 489 [114–4,201]343[0–1256]10 [0–22]179 [171–267] 5,491 [2,086–8,632]2,876 [2456–4126]21 [14][30]232 [132–320] 2,592 [2,100–5,974]2,560 [82–4063]17 [1][20]209 [70–239] 3,388 [2,790–5,796]310[116–702]2 [2][8]217 [209–292] 0.106<0.0010.0080.615
*

Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA.

Data presented as n (%) and analyzed by Chi square.

Abbreviations: EONS, early-onset neonatal sepsis; IAI, intra-amniotic infection; LDH, lactate dehydrogenase; WBC, white blood cell; HCA, histological chorioamnionitis; ANC, absolute neutrophil count; ABC, absolute band count; I:T ratio, ratio of immature-to-total neutrophils.