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. 2013 Feb 20;8(2):e55941. doi: 10.1371/journal.pone.0055941

Table 5. Comparison of n−6/n−3 ratios between wild-type and mfat-1 transgenic lamb.

Organs or Tissues n−6/n−3 Ratioa
Wild-type Transgenic
Heart 2.28±0.01 0.93±0.02**
Liver 1.56±0.05 0.66±0.04**
Spleen 3.04±0.23 1.50±0.16**
Lung 2.66±0.46 1.40±0.12*
Kidney 2.45±0.05 1.36±0.15**
Brain 0.42±0.01 0.32±0.01**
Ear 2.89±0.02 1.18±0.25**
Tongue 1.66±0.13 1.25±0.02*
Tail 4.60±1.14 2.08±0.63*
Muscle 2.63±0.05 1.24±0.06**

Ratio of n−6/n−3 fatty acid was calculated from n−6 fatty acids [linoleic acid (LA, 18∶2n−6) and arachidonic acid (AA, 20∶4n−6)] versus n−3 fatty acids [α-linolenic acid (ALA, 18∶3n−3), eicosapentaenoic acid (EPA, 20∶5n−3), and docosahexaenoic acid (DHA, 22∶6n−3)]. Each value represents the mean ± standard deviation from three replicated sample measurements of each tissue.

a

Statistical analysis using the two tailed student t-test. Significant differences between the wild-type and the transgenic lamb samples were marked (*P<0.05; **P<0.01).