Table 8.
ligand | epoxide | oxidant | time (h) | yield (%) | ee (%) |
---|---|---|---|---|---|
8g | THP | 18 | 98 | 95 | |
8f | THP | 20 | 94 | 92 | |
8g | THP | 20 | 60 | 90 | |
8d | TBHP | 20 | 92 | 96 | |
8d | CHP | 22 | 77 | 64 | |
8d | CHP | 40 | 95 | 85 | |
8d | CHP | 36 | 84 | 82 | |
8d | CHP | 40 | 95 | 85 | |
8d | CHP | 40 | 92 | 50 | |
8d | TBHP | 36 | 44 | 62 | |
8d | CHP | 36 | 92 | 85 | |
8d | CHP | 46 | 94 | 66 (de) | |
8h | CHP | 42 | 82 | 76 | |
8d | TBHP | 17 | 13 | 43 |