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. Author manuscript; available in PMC: 2014 Feb 15.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Dec 27;431(3):617–622. doi: 10.1016/j.bbrc.2012.12.083

Figure 1. The autophagy pathway was bioinformatically predicted to be regulated by mir-30d.

Figure 1

(A) Two mRNA expression profiling datasets of NCI60 were retrieved from Cell Miner database (left panel: U133A) and (right panel: U133 plus 2.0). Using GSEA algorithm, the molecular pathways that were significantly enriched based on mir-30d expression were predicted. The autophagy pathway was identified. Enrichment score (ES) and p value are shown as indicated. (B) Using TargetScan algorithm, multiple genes in the autophagy pathway was predicted to be regulated by mir-30d (indicated as pink).