Table 1. Baseline Patient Characteristics.
LEDD – Levodopa equivalent daily dose (mg) a dose of 100 mg of levodopa is equal to 125 mg of controlled-release levodopa is equal to 10 mg of bromocriptine is equal to 1 mg of pergolide is equal to 4 mg of ropinrirole is equal to 100 mg of amantadine is equal to 333 mg of comtan, is equal to 1 mg pramipexole is equal to 80 mg of stalevo. [31]
| Patient | Age (yrs) | Sex | Duration of PD (yrs) | UPDRS III off | UPDRS III on | % Change UPDRS | UPDRS Total | Hoehn Yahr off | LEDD (mg) |
|---|---|---|---|---|---|---|---|---|---|
| 1* | 66 | F | 15 | 40 | 9 | 77.50 | 63 | 3.0 | 1258 |
| 2 | 58 | M | 12 | 60 | 18 | 70.00 | 97 | 3.0 | 1750 |
| 3 | 50 | M | 8 | 32 | 12 | 62.50 | 48 | 2.0 | 1090 |
| 4 | 57 | M | 6 | 37 | 16 | 56.76 | 56 | 5.0 | 2394 |
| 5 | 64 | F | 12 | 55 | NA | NA | NA | 3.0 | 1002 |
| 6** | 59 | M | 15 | 44 | 22 | 50.00 | 81 | 3.0 | 1140 |
| 7** | 58 | M | 8 | 46 | 6 | 86.96 | 94 | 4.0 | 1560 |
| 8 | 62 | F | 11 | 54 | 13 | 75.93 | 94 | 5.0 | 862 |
| 9 | 66 | M | 12 | 44 | 21 | 52.27 | 77 | 3.0 | 1516 |
| 10 | 62 | F | 7 | 34 | 23 | 32.35 | 69 | 4.0 | 340 |
| 11 | 60 | M | 15 | 41 | 25 | 39.02 | 66 | 2.0 | 1376 |
| 12 | 54 | M | 7 | 27 | 11 | 59.26 | 45 | 2.0 | 2065 |
| 13 | 56 | F | 8 | 54 | 9 | 83.33 | 97 | 4.0 | 1354 |
| 14 | 57 | F | 9 | 58 | 25 | 56.90 | 89 | 4.0 | 1380 |
| 15 | 65 | F | 10 | 31 | 13 | 58.06 | 52 | 2.0 | 825 |
| 16 | 67 | F | 24 | 50 | 16 | 68.00 | 89 | 5.0 | 1180 |
| 17 | 55 | M | 9 | 46 | 23 | 50.00 | 70 | 3.0 | 1635 |
| Mean (+/−SD) | 59.8 (4.8) | 9M/8F | 11.1 (4.4) | 43.3 (11.2) | 15.9 (7.4) | 60.2 (19.8) | 71.4 (20.3) | 3.4 (1.1) | 1337 (482) |
Excluded from the analysis (patient explanted at month 2)
Follow-up data missing