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Biodistribution of 64Cu-Comb and 64Cu-CANF-Comb in CWR22 tumor model following intravenous injection (n=4/group). (A) 64Cu-Comb showing low tumor accumulation but high liver uptake. (B) 64Cu-CANF-Comb showing high tumor localization and superior pharmacokinetics relative to 64Cu-Comb with high blood retention and low hepatic burden.
