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Constants for inhibition of A. gambiae AChE2 by carbamates and organophosphates*
| compounds | Ka (μM) | k2 (min−1) | ki (μM−1min−1) |
|---|---|---|---|
| eserine | 3.60 ± 2.81 | 3.97 ± 0.97 | 1.173 ± 0.043 |
| carbaryl | 2.90 ± 0.27 | 0.72 ± 0.07 | 0.245 ± 0.093 |
| paraoxon | 34.4 ± 0.7 | 0.36 ± 0.01 | 0.029 ± 0.011 |
| malaoxon | 97.0 ± 16.0 | 1.71 ± 0.24 | 0.018 ± 0.007 |
Correlation coefficients (r2) of the linear regressions (p-value < 0.0001) are greater than 0.99.
