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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Pharm Res. 2012 Nov 28;30(3):889–898. doi: 10.1007/s11095-012-0930-2

Table I.

Observed mean hematological and biochemical parameters in rats at healthy state (prior to iron free diet plan) and at anemic condition

Parameter Basal values Anemic condition
Hematological parameters
Hemoglobin (g/dl) 14.31 ± 2.47 10.58 ± 1.61
HCT (%) 41.35 ± 8.33 32.4 ± 3.72
MCV (fl) 56.25 ± 2.12 38 ± 2.86†††
MCH (pg) 19.56 ± 1.57 12.4 ± 1.22†††
MCHC (g/dl) 34.83 ± 1.61 28.22 ± 2.24††
RBC (1012/l) 8.40 ± 0.83 6.61 ± 0.75
RDWc (%) 16.71 ± 2.22 28.33 ± 2.73†††
Biochemical parameters
Serum Iron (μg/dl) 179.53 ± 15.84 83.46 ± 17.02†††
TIBC ((μg/dl) 374.86 ± 56.33 483.84 ± 57.91
% TS 46.28 ± 7.04 16.59 ± 2.11††
Lipid peroxidation [equivalent to MDA conc (nmol/ml)] 8.58 ± 1.72 14.51 ± 3.92
*

The difference in all parameters in rats between healthy (basal values) and anemic conditions is statistically significant.

p<0.05

††

p<0.001

†††

p<0.0001