Table 1.
Baseline Characteristics According to Atrial Fibrillation Status, Atherosclerosis Risk in Communities (ARIC) Study and Cardiovascular Health Study (CHS)a
| ARIC | Incident AF through 2001, ARIC | CHS | Incident AF through 2006, CHSb | |||
|---|---|---|---|---|---|---|
| Total sample (n=15439) |
No (n=14545) |
Yes (n= 894) |
Total sample (n= 5479) |
No (n= 4021) |
Yes (n= 1458) |
|
| Age, mean (SD), y | 54.2 (5.8) | 54.0 (5.7) | 57.5 (5.3) | 72.7 (5.5) | 72.5 (5.5) | 73.4 (5.6) |
| Female | 8524 (55.2) | 8147 (56.0) | 377 (42.2) | 3189 (58.2) | 2396 (59.6) | 793 (54.4) |
| Black race | 4107 (26.6) | 3945 (27.1) | 162 (18.1) | 845 (15.4) | 689 (17.1) | 156 (10.7) |
| Current cigarette smoking | 4044 (26.2) | 3752 (25.8) | 284 (31.8) | 658 (12.0) | 502 (12.5) | 156 (10.7) |
| Body mass index, mean (SD) (kg/m2) | 27.7 (5.4) | 27.6 (5.3) | 28.9 (6.1) | 26.7 (4.7) | 26.6 (4.7) | 26.9 (4.8) |
| Heart rate, mean (SD), (bpm)c | 66.3 (10.3) | 66.2 (10.2) | 66.7 (11.3) | 65.0 (11.4) | 65.3 (11.6) | 64.1 (11.0) |
| ECG-based LVH | 338 (2.2) | 292 (2.0) | 46 (5.2) | 280 (5.1) | 205 (5.1) | 75 (5.1) |
| Diabetes | 1816 (11.8) | 1633 (11.2) | 183 (20.5) | 878 (16.1) | 620 (15.5) | 258 (17.7) |
| Hypertension | 5353 (34.7) | 4892 (33.6) | 461 (51.6) | 3207 (58.5) | 2275 (56.6) | 932 (63.9) |
| Coronary heart disease | 737 (4.8) | 626 (4.3) | 111 (12.4) | 1049 (19.1) | 697 (17.3) | 352 (24.1) |
| Heart failure | 716 (4.6) | 613 (4.2) | 103 (11.5) | 211 (3.1) | 129 (3.2) | 82 (5.6) |
| Use of beta-blockers | 1611 (10.4) | 1415 (9.7) | 196 (21.9) | 695 (12.7) | 482 (12.0) | 213 (14.6) |
| Use of anti-arrhythmics | 115 (0.7) | 80 (0.6) | 35 (3.9) | 172 (3.1) | 91 (2.3) | 81 (5.6) |
Abbreviations: AF, atrial fibrillation; LVH, left ventricular hypertrophy based on Cornell criteria
a
Data are presented as No. (%) of participants unless otherwise stated
b
The second CHS cohort had by design 3 years shorter follow-up than the first CHS cohort
c
Heart rate was determined based on 12-lead ECG at baseline