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Hemagglutinin inhibition (HAI) titers in ferrets pre-challenge and viral load in nasal washes of ferrets 4 days post challenge with H1N1.
| Group | HAI
|
Viral load in nasal discharge (TCID50 /ml)a | |
|---|---|---|---|
| GMT | Range | ||
| Ad5 [E1-, E2b-]-HA+NA | 452.5 | 1:160–1:640 | <LDb |
| Ad5 [E1-, E2b-]-HA | 640 | 1:320–1:1280 | <LD |
| Saline | <1:40 | NA | 5.7;5.0;4.5;4.7 |
Challenge virus was Influenza H1N1 A/CA/07/2009.
LD, limit of detection.
