Table 3.
Cox proportional hazard ratio estimates for the effect of sarcopenia on 3-year mortality after adjustment for other covariates
Univariate |
Multivariate |
|||
---|---|---|---|---|
Hazard ratio (95 % CI) |
P value | Hazard ratio (95 % CI) |
P value | |
Sarcopenia | 1.68 (1.34–2.11) | <0.001 | 1.63 (1.28–2.07) | <0.001 |
Age at surgery (years) | 1.01 (1.00–1.02) | 0.02 | 1.01 (1.00–1,03) | 0.01 |
Weight (kg) | 0.99 (0.99–1.00) | 0.55 | – | – |
Male gender | 1.16 (0.94–1.43) | 0.16 | – | – |
Tumor size (cm) | 1.13 (1.07–1.19) | <0.001 | 1.13 (1.06–1.20) | <0.001 |
Poorly differentiated tumor | 1.75 (1.40–2.12) | <0.001 | 1,76 (1.42–2.17) | <0.001 |
Nodal metastasis | 2.06 (1.55–2.74) | <0.001 | 1.73 (1.29–2.32) | <0.001 |
Vascular infiltration | 1.57 (1.27–1.93) | <0.001 | 1.25 (1.05–1.55) | <0.001 |
Positive margins | 1.66 (1.33–2.06) | <0.001 | 1.46 (1.17–1.82) | <0.001 |
Pancreatoduodenectomy (vs. distal pancreatectomy) |
1.07 (0.78–1.45) | 0.68 | – | – |
Clavien–Dindo grade ≥3 complications |
1.70 (1.32–2.19) | <0.001 | 1.88 (1.44–2.44) | <0.001 |
Race (reference: White) | ||||
African American | 1.02 (0.70–1.47) | 0.93 | – | – |
Other race | 0.58 (0.35–0.95) | 0.03 | 0.66 (0.40–1.09) | 0.11 |