FIG. 2.

Gene expression profile in hBM-MSC and normal human dermal fibroblasts (NHDF) and their relative exosomes. (A) Representative scatter plot generated by the polymerase chain reaction (PCR) array to determine the expression profile of genes involved in the insulin-signaling pathway in hBM-MSC and their corresponding exosomes. (B) Reverse transcription (RT)-PCR analysis for insulin-like growth factor-1 (IGF-1) and IGF-1 receptor (IGF-1R) on hBM-MSC and their respective exosomes and (C) on NHDF and their respective exosomes. (D) RT-PCR analysis for human IGF-1R full length (transcript of 4122 bp) in human exosomes (hExo). RT- represents negative controls obtained by omitting reverse transcriptase enzyme.