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. Author manuscript; available in PMC: 2013 Jul 20.
Published in final edited form as: J Mol Biol. 2012 May 1;420(4-5):384–399. doi: 10.1016/j.jmb.2012.04.025

Fig. 2.

Fig. 2

CD characterization of highly conserved mutations. (a) The circular dichroism spectra of wild type and consensus variants of TIM. All have similar ellipticity when normalized for concentration except W90Y, which may be partially unfolded. (b) The CD thermal melts indicate that four individual consensus variants are more stable than wild type, but the remaining two are less stable.