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. 2012 Dec 7;22(6):1097–1111. doi: 10.1093/hmg/dds515

Figure 3.

Figure 3.

gpc5 morpholinos inhibit neural tube closure in X. tropicalis embryos. (A and B) Tailbud stage X. tropicalis embryos injected with gpc5-MOs (B) or left uninjected (A). (C and D) Stage 22/23 embryos injected with control morpholino (co-MO; C) or 10 ng gpc5-MO (D). Arrow in (D) indicates open neural tube. (E–G) Embryos injected with a co-MO (E) or gpc5-MO (F and G) were stained for pax6 by in situ hybridization. Arrow in (G) indicates open neural tube. Dorsal views, anterior is toward the top in (C, D) and toward the left in (A, B; E–G).