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Dose–response curves for G oxidation products with different oxidants. DNA was treated with (a) γ-radiation, (b) ONOO–, (c) 1O2 from photooxidation of rose bengal, and (d) SIN-1, and the G oxidation products 8-oxodG, Sp, Gh, and Ox were quantified as described in Experimental Procedures. Data are plotted as the lesion level without exponential scaling on the Y-axis, with the exponential scaling noted in the inset. Data represent the mean ± SD.
