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. 2013 Jan 17;15(3):370–381. doi: 10.1093/neuonc/nos308

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© The Author(s) 2013. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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Fig. 1. — Kaplan-Meier analysis of overall survival (OS, A, C, E) and progression-free survival (PFS, B, D, F) comparing (A and B) IHC <30% (solid) to IHC ≥30% (dashed), (C and D) MSP methylated (solid) to MSP unmethylated (dashed), and (E and F) BiSEQ ≥3 (hypermethylated, solid) to BiSEQ <3 (hypomethylated, dashed). A and B, IHC <30% showed improved outcomes compared to IHC ≥30% (OS, log rank P < .0001; PFS, log rank P < .0001). C and D, MSP methylated (solid) showed improved outcomes compared to MSP unmethylated (dashed) (OS, log rank P < .0001; PFS, log rank P < .0001). E and F, BiSEQ ≥3 (solid) showed improved outcomes compared to BiSEQ <3 (dashed) (OS, log rank P < .0001; PFS, log rank P = .0001).