Figure 6. Effect of pH on UCP3 degradation in vitro.
(A) Degradation of UCP3 in brown adipose tissue mitochondria in vitro at different pH values. Symbols: -26S (open circles): all required in vitro components minus the 26S proteasome. Closed symbols: all required in vitro components, varying pH. (B) Area under the curve values of the individual experiments in (A). Data represent means ± SEM (n = 3–6).