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. 2013 Feb 21;9(2):e1002899. doi: 10.1371/journal.pcbi.1002899

Table 6. Description of the dataset used in the current study (Obtained from Virco).

Target Amino acids Binding Site Drug Class Drugs Mutant Sequences Data points Mean number of mutations
Reverse Transcriptase 400* Orthosteric NRTI 8 10,501 72,727 22 (±9)
Reverse Transcriptase 400* Allosteric NNRTI 4 10,723 35,249 22 (±9)
Protease 99 Orthosteric PI 9 27,081 180,162 10 (±6)
*

For Reverse Transcriptase only the first 400 amino acids were sequenced. The total size of the dataset is unlike any other dataset used in PCM. The number of mutations shown in the last column is the average per sequence and standard deviation when compared to HXB2.