Figure 3. Power to identify regions containing causative mutations.

(a) The power of the logistic regression in GWAS and resequencing studies at significance threshold α = 10⁻⁸. (b) The power of Madsen and Browning's [16] test (at α = 10⁻⁶). (c) The power of Li and Leal's [15] multiple-marker test (at α = 10−6). (d) Power (at α = 10−6) using the SKAT software package, applied to data from recombining regions. (e) Power (at α = 10⁻⁶) using the SKAT software package, applied to data from non-recombining regions. (f) The power of the ESM test (at α = 10⁻⁶, see Methods) in GWAS and resequencing studies.