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. 2013 Feb 21;8(2):e57241. doi: 10.1371/journal.pone.0057241

Table 1. Clinical findings in 415 patients with Chiari malformation type I.

CMI
Number of patients 415
Sex (M/F) 122/293
Age (y) 42.2±50.9
Age at diagnosis 30.6±58.7/323
Hydrocephalus 57/377 (15.1%)
Syringomyelia 133/379 (35.1%)
Intracranial Hypertension 20/376 (5.3%)
Retrocurved Odontoid 40/352 (11.4%)
Basilar impression 11/382 (2.3%)
Platibasia 8/382 (2.1%)
Klippel-Feil Malformation 3/377 (0.8%)
Other Craniocervical Malformations 24/377 (6.4%)
SIGNS AND SYMPTOMS
Time elapsed from onset (mo) 113.3±59.4/323
Headache 246/356 (69.1%)
Occipital Headache/Cervicalgia 97/224 (43.3%)
Cough Headache 87/358 (24.3%)
Dizziness 128/365 (35.1%)
Vertigo 82/365 (22.5%)
Visual Alterations 71/364 (19.5%)
Nystagmus 41/276 (14.8%)
Kyphoscoliosis 30/160 (18.7%)
Fatigue 102/363 (28.1%)
Instability 117/364 (32.1%)
Sensory Loss 108/364 (29.7%)
Motor Weakness 123/366 (33.6%)
Dysphagia 67/365 (18.3%)
Dysphonia 16/365 (4.4%)
Gait Disturbances 73/364 (20.0%)
Paresthesia Upper Limbs 112/365 (30.7%)
Paresthesia Lower Limbs 47/366 (12.9%)
Upper Limb Pain 47/365 (12.9%)
Lower Limb Pain 16/365 (4.4%)
Neck Pain 169/366 (46.2%)
Difficulty Swallowing 66/365 (18.1%)
Anxiety 38/360 (10.5%)
Depression 33/361 (9.1%)
Neurofibromatosis type 1 45/382 (11.8%)
TREATMENT
Posterior fossa reconstruction 210/376 (55.8%)