Table 5. A multiple linear regression model for the meTIMP/6-TGN concentration ratio.^a .

Parameter		Estimate	95% CI	P
Intercept		0.44	−3.32–4.20	0.82
CD1D		−1.04	−1.81–−0.27	0.01
TUSC2		1.02	0.39–1.64	0.002
PLCB2		1.47	0.42–2.52	0.007
NT5E		−0.29	−0.64–0.07	0.11
TPMT		1.31	0.28–2.34	0.01
Glucocorticosteroids	Yes	0.57	0.14–0.99	0.01

^aThe regression model is based on the expanded patient cohort (n = 54), using the natural logarithm of the meTIMP/6-TGN concentration ratio as dependent variable and the gene expression levels (dC_T values) of CD1D, PLCB2, NT5E, TPMT, TUSC2, and glucocorticosteroid therapy as independent variables. A higher dC_T value is associated with a lower gene expression level. R² = 0.46, P = 3×10⁻⁵.