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. 2013 Feb 21;8(2):e56989. doi: 10.1371/journal.pone.0056989

Table 7. A multiple linear regression model for the concentration of 6-TGN.a .

Parameter Estimate 95% CI P
Intercept 0.08 −0.16–0.31 0.52
TUSC2 −0.27 −0.46–−0.07 0.008
Glucocorticosteroids Yes −0.22 −0.41–−0.04 0.02
5-ASAxGlucocorticosteroids Yes −0.11 −0.25–0.03 0.14
a

The regression model is based on the expanded patient cohort (n = 54), using the natural logarithm of the 6-TGN concentration as dependent variable and the gene expression level (dCT value) of TUSC2, and glucocorticosteroid and 5-ASA therapy as independent variables. A higher dCT value is associated with a lower gene expression level. R2 = 0.27, P = 0.001.