Table 3. Drug resistance profiles of K. pneumoniae isolates grouped by clonal complex.
Clonal complex (No. of isolates) | Drug resistance types, No. (%) of isolates | Drug resistance, No. (%) of isolates | ||||||||||||
MDR | XDR | PDR | Penicillin | Non-extended spectrum cephalosporins | Extended spectrum cephalosporins(bla CTX-M) | Extended spectrum cephalosporins(bla TEM/bla SHV) | Cephamycins | Carbapenems | Monobactams | Fluoroquinolones | Aminoglycosides | Folate pathway inhibitors | Nitrofurantoin | |
CC1 (3) | 2(66.7) | 1(33.3) | 0 | 3 (100.0) | 3 (100.0) | 3(100.0) | 2 (66.7) | 3 (100.0) | 1(33.3) | 3(100.0) | 3(100.0) | 2 (66.7) | 2 (66.7) | 3(100.0) |
CC12 (1) | 1(100.0) | 0 | 0 | 1(100.0) | 0 | 0 | 0 | 1(100.0) | 0 | 0 | 0 | 0 | 0 | 1(100.0) |
CC23 (82) | 52(63.4) | 17(20.7) | 3(3.7) | 82 (100.0) | 39 (47.6) | 33 (40.2) | 26 (31.7) | 61(74.4) | 6(7.3) | 39(47.6) | 34(41.5) | 41(50.0) | 42(51.2) | 73(89.0) |
CC29 (1) | 1(100.0) | 0 | 0 | 1(100.0) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1(100.0) |
CC37 (8) | 4 (50.0) | 2 (25.0) | 0 | 8(100.0) | 6 (75.0) | 5 (62.5) | 6 (75.0) | 4(50.0) | 0 | 6(75.0) | 3(37.5) | 5(62.5) | 4(50.0) | 7(87.5) |
CC86 (3) | 2(66.7) | 0 | 0 | 3(100.0) | 0 | 0 | 0 | 2(66.7) | 0 | 0 | 0 | 0 | 0 | 1(33.3) |
CC101 (2) | 1(50.0) | 0 | 0 | 2(100.0) | 1(50.0) | 1(50.0) | 1(50.0) | 1(50.0) | 0 | 1(50.0) | 0 | 1(50.0) | 1(50.0) | 2(100.0) |
CC147 (11) | 7 (63.6) | 4 (36.4) | 0 | 11(100.0) | 8 (72.7) | 4 (36.4) | 5 (45.5) | 7 (63.6) | 1(9.1) | 5 (45.5) | 11(100.0) | 10(90.9) | 11(100.0) | 11(100.0) |
CC526-928 (2) | 1 (50.0) | 0 | 0 | 2(100.0) | 2(100.0) | 2(100.0) | 2(100.0) | 0 | 0 | 2(100.0) | 2(100.0) | 2(100.0) | 2(100.0) | 2(100.0) |
CC536-856 (1) | 0 | 0 | 0 | 1(100.0) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CC584 (1) | 1(100.0) | 0 | 0 | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 0 | 0 | 1(100.0) | 0 | 1(100.0) | 1(100.0) | 1(100.0) |
CC857 (1) | 1(100.0) | 0 | 0 | 1(100.0) | 0 | 0 | 0 | 1(100.0) | 0 | 0 | 0 | 0 | 0 | 1(100.0) |
CC889-7 (1) | 0 | 1(100.0) | 0 | 1(100.0) | 0 | 0 | 0 | 1(100.0) | 0 | 0 | 0 | 0 | 0 | 1(100.0) |
Singletons(46) | 31(67.4) | 9(19.6) | 0 | 45(97.8) | 26 (56.5) | 21(45.7) | 19(41.3) | 27(58.7) | 3(6.5) | 26(56.5) | 19(41.3) | 28(60.9) | 31(67.4) | 41(89.1) |
Total(163) | 104(63.8) | 34(20.9) | 3(1.8) | 162(99.4) | 86(52.8) | 70(42.9) | 62(38.0) | 108(66.3) | 11(6.7) | 83(50.9) | 72(44.2) | 90(55.2) | 94(57.7) | 145(89.0) |