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. 2013 Feb 21;8(2):e57099. doi: 10.1371/journal.pone.0057099

Table 1. Effect of SC-1 on the Tumor Take Rate of the Seven Colon Tumor Lines of the NCI60 Panel*.

Number of Cells Inoculated
Cell Line 100 1000 10000
Control SC-1 Control SC-1 Control SC-1
COLO 205 0/5 0/5 1/4 1/5 1/5 4/5
HCC-2998 0/5 0/5 0/5 0/5 2/5 2/5
HCT-15 0/5 0/5 0/5 0/5 0/5 0/5
HCT-116 1/5 0/5 3/5 2/5 3/5 5/5
HT29 0/5 2/5 0/5 3/5@ 3/5 5/5
KM12 0/5 0/5 0/5 0/5 0/5 1/5
SW-620 0/5 0/5 1/5 0/5 1/5 2/5
TOTAL 1/35 2/35 5/34 6/35 10/35 & 19/35
*

Female NOD.SCID mice were inoculated s.c. with bulk population colon cell lines treated for 5 days as indicated with control media or media containing 0.1 µM SC-1.

@Significant difference between control and SC-1 treated groups in the HT29 colon tumor line, 0.0375<p<0.05.

&

Significant difference between control (10/35) and SC-1 (19/35) treated group for 7 colon tumor lines, p = 0.04.