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. 2013 Feb 21;8(2):e57099. doi: 10.1371/journal.pone.0057099

Table 2. Calculated Time to 1000 mg Tumor Volume in 5 Colon Lines Forming Tumors*.

Day#
Cell Line Control SC-1
COLO 205 513 101
HCC-2998 184 139
HCT-116 48 45
HT29 185 32
SW-620 126 98
*

NOD.SCID mice injected s.c. with treated colon tumor lines at 10,000 cells/inoculum. Linear curves were fitted to population averages plotted for time (up to 120 days) vs. calculated mean tumor size (range of r: 0.73–0.90). Because mice injected with KM12 treated cells formed only one tumor in SC-1 conditions and no tumors under control conditions, this result was excluded from the analysis. Colon tumor lines were treated with 0.1 µM SC-1 or control media five days prior to inoculation.

#

Mean day±S.E. was 211±79 for control vs. 83±19 for SC-1 treated (n = 5, p = 0.16, Student’s paired t test).