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. 2013 Feb 21;8(2):e54896. doi: 10.1371/journal.pone.0054896

Figure 7. Determination of steady-state kinetic parameters of Gcn5-mediated acetylation of H3K14ac for individual and total lysine residues (i.e. K9, K18, and K23).

Figure 7

The left panels (A)-(D) show the data when titrating H3K14ac; and the right panels (E)-(H) show the data when titrating acetyl-CoA. The apparent kinetic parameters are listed in Table 2. When fitting data from (A) to (D), the Hill coefficient (nH) is approximately equal to 2, suggesting H3K14ac could form a dimer to be further acetylated.