Fig. 1.

Effects of taxifolin glycoside on hERG K⁺ currents. (A) Representative hERG K⁺ current traces in control and 30µM taxifolin glycoside-treated sample were recorded using a two-stage voltage protocol (upper panel). (B) Normalized I-V relationships for current measured at the peak of repolarizing tail current (I_tail) in the absence and the presence of 30 µM taxifolin glycoside. (C) Concentration-response relationships for taxifolin glycoside in I_tail. Data were fitted with the Hill equation and EC₅₀ was 9.6±0.7µM (n=5).