Fig. 7.
Effects of MPTP (20 mg/kg, s.c) on tetrahydrobiopterin (BH4) concentration in brain regions. The endogenous level of BH4 in mice brain regions ((A) striatum, (B) substantia nigra, (C) hippocampus) were measured by LC-MS/MS in three different mice strains. (D) Internal calibration for BH4. Data is expressed as mean±standard error of the mean (n=5).
