TABLE E4.

Prediction of asthma susceptibility using 6 SNPs in GSDMB, IL33, IL1RL1, TSLP, IL13, and HLA-DRA

SNP	Gene	SARP/CSGA/CAG			TENOR		AUC
		P value	Deviance (%)*	AUC	P value	Deviance (%)
rs2872507	GSDMB	.0063	0.25%		.11	0.12%
rs3939286	IL33	.033	0.15%		.061	0.17%
rs13431828	IL1RL1	2.43E-04	0.46%		.03	0.23%
rs1837253	TSLP	4.78E-04	0.41%		.13	0.11%
rs20541	IL13	.22	0.05%		.0016	0.47%
rs2395185	HLA-DRA	3.84E-04	0.42%		6.47E-05	0.78%
All 6 SNPs†		1.12E-09	1.76%	0.59	8.97E-07	1.85%	0.592
Genetic Score‡		1.31E-11	1.56%	0.581	7.65E-09	1.60%	0.582

AUC, Area under the receiver operating characteristic curve.

^*Percentage of deviance explained by SNPs in logistic regression model adjusted for age and sex.

^†All 6 SNPs were included in the logistic regression model.

^‡A single score determined by counting the number of risk SNPs of 6 SNPs.