Table 2.

Area under the curve of pharmacodynamic effect vs. time (0–2 h after dosage) plot

	Mean ± SD (N = 8)		P value*
	Placebo	Curcuminoid/piperine
Self-rated sedation	18.8 ± 26.2	4.9 ± 11.4	0.05
Observer-rated sedation	12.1 ± 26.0	3.4 ± 6.4	0.53
DSST	−13.4 ± 18.5	−16.7 ± 19.7	0.61
EEG beta amplitude
Raw uncorrected	87.2 ± 12.4	88.7 ± 11.1	0.08
Baseline corrected	0.5 ± 3.5	3.9 ± 7.6	0.70

^*Statistical comparisons were made with the Student's paired t-test on rank-transformed values.