Figure 7.

BD750 attenuates the DNFB-induced DTH reaction. Mice were treated i.p. with different doses of BD750, CsA or vehicle alone beginning on day 6 for three consecutive days. Then the mice were challenged with DNFB on day 7. The thickness of both left and right ears and the weight of ear patch were measured 48 h post challenge. Ear swelling was calculated as the increase in ear thickness (A) and ear patch weight (B) between the left (DNFB-untreated) and right (DNFB-treated) ear. Results presented are mean ± SEM, n = 3, *P < 0.05 versus control group (treated with vehicle).