Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Visual predictive check of plasma concentration versus time normalized to a therapeutic dose of 25 mg/m2 for cycle 1 (left) and cycle 2 (right) from 0 to 25 h (top) and 0 to 600 h (bottom) from previous dose. Circle observed concentration; red line median; green dotted line 5th and 95th percentile; LLOQ: lower limit of quantification
