Fig. 4.

VSLI and VCR antitumor activity in Namawala (a) and LX-1 (b) tumor bearing mice. Namawala (human lymphoma model) or LX-1 (human SCLC model) tumor cells were implanted subcutaneously into SCID mice. Mice received vehicle (dotted line), VCR (dashed lines), or VSLI (solid lines) on days 11, 18 and 25 post-implantation. Data represent mean ± SD, N = 5–10. The symbols indicate the following treatments: Vehicle-treated control (−), vincristine 0.5 mg/kg (+), 1.0 mg/kg (open circle), 1.5 mg/kg (open square); VSLI 1.0 mg/kg (filled circle), 1.5 mg/kg (filled square), 2.5 mg/kg (filled diamond)