Table 1.
Pharmacokinetic parameters in VSLI- and VCR-treated rats at 2.0 mg/m2
| Formulation | C max (ng/mL) | AUCinf (ng·h/mL) | t 1/2λ1 (h) | t 1/2λz (h) | Cl (mL/h/m2) | V ss (mL/m2) |
|---|---|---|---|---|---|---|
| VSLI | 5,662 | 63,438 | 6.9 | NAa | 32 | 383 |
| VCR | 148 | 806 | 0.2 | 36.5 | 2,488 | 113,513 |
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