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Comparison of tissue exposure to vincristine following administration of either VSLI or VCR
| AUCinf, ng eq· h/g | ||||
|---|---|---|---|---|
| Spleen | Liver | Lymph node | Bone marrow | |
| VSLI | 381,154 | 28,202 | 66,333 | 40,936 |
| VCR | 30,765 | 6,496 | 6,420 | 17,767 |
| Ratio VSLI/VCR | 12.4 | 4.3 | 10.3 | 2.3 |
