Table 5.
C max (ng/mL) | T max (h) | AUC0–last (ng h/mL) | AUC0-inf (ng h/mL) | t 1/2 (h) | CL (mL/h) | Vd (mL) | Vdss (mL) | MRT0–inf (h) | |
---|---|---|---|---|---|---|---|---|---|
N | 13 | 13 | 13 | 12 | 12 | 12 | 12 | 12 | 12 |
Mean | 1,220 | – | 13,732 | 14,566 | 7.66 | 345 | 3,569 | 2,914 | 9.63 |
SD | 229 | – | 5,666 | 6,368 | 3.18 | 177 | 1,924 | 1,219 | 4.44 |
CV % | 18.8 | – | 41.3 | 43.7 | 41.5 | 51.2 | 53.9 | 41.8 | 46.1 |
Min | 919 | 1.08 | 6,975 | 7,036 | 4.49 | 148 | 1,540 | 1,803 | 5.38 |
Median | 1,230 | 1.25 | 13,502 | 13,680 | 6.61 | 302 | 3,254 | 2,601 | 8.43 |
Max | 1,720 | 4.17 | 24,036 | 26,074 | 12.6 | 783 | 7,754 | 6,500 | 17.7 |