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. Author manuscript; available in PMC: 2013 Feb 22.
Published in final edited form as: Mol Cell Proteomics. 2006 Dec 27;6(3):413–424. doi: 10.1074/mcp.M600437-MCP200

Fig. 7. Protein kinase phylogenetic tree.

Fig. 7

Relationships between members of the protein kinase superfamily (kinome dendrogram reprinted with permission from Cell Signaling Technology, Inc. and Manning et al. 20)) are shown. Group names are: AGC containing cAMP-dependent protein kinase (PKA), cGMP-dependent protein kinase (PKG), and protein kinase C (PKC); CAMK calcium/calmodulin-dependent protein kinase; CK1 casein kinase 1; CMGC containing CDK, mitogen-activated protein kinase (MAPK), glycogen synthase kinase 3 (GSK3), and CDC-like kinase (CLK) families; STE homologs of the yeast Sterile kinases; TK tyrosine kinase; TKL tyrosine kinase-like. Insets highlight several atypical and mouse-specific kinases in the AfCS collection. The murine orthologs of all kinases highlighted red are represented in the AfCS plasmid database and are available through the ATCC (see Supplemental Table 4 for clone IDs).