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. Author manuscript; available in PMC: 2013 Feb 22.
Published in final edited form as: J Pharmacol Sci. 2013 Jan 22;121(2):95–102. doi: 10.1254/jphs.12169fp

Fig. 2.

Fig. 2

Dose–response curve for acetylcholine (A)- and sodium nitroprusside (B)-induced vasorelaxation of the thoracic aorta. Acetylcholine-induced relaxation was significantly reduced in NS + HF diet–fed DSS rats. In these animals, impairment of acetylcholine-induced relaxation was normalized by treatment with olmesartan but not with hydralazine. Sodium nitroprusside–induced vasorelaxation was not different among the groups. *P < 0.05: NS/DSS rats vs. NS + HF/DSS rats, NS + HF/DSS rats + olmesartan or NS + HF/DSS rats + hydralazine; †P < 0.05: NS + HF/DSS rats vs. NS + HF/DSS rats + olmesartan or NS + HF/DSS rats + hydralazine.