Table 2.
Variable | Depression Status | p-value | |
---|---|---|---|
Depressed (PHQ ≥10) n=118 | Not Depressed (PHQ<10) N=641 | ||
n-3 Fatty Acids | |||
Alpha-linolenic acid | 0.2% (±0.4) | 0.1% (±0.3) | 0.166 |
Eicosapentaenoic acid (EPA) | 0.3% (±0.4) | 0.3% (±0.5) | 0.260 |
Docosapentaenoic acid (n-3) | 1.5% (±0.6) | 1.7% (±0.6) | 0.006 |
Docosahexaenoic acid (DHA) | 2.6% (±1.2) | 3.0% (±1.5) | 0.008 |
EPA+DHA | 2.9% (±1.5) | 3.3% (±1.8) | 0.002 |
Total n-3 | 4.8% (±1.8) | 5.5% (±2.0) | 0.001 |
n-6† Fatty Acids | |||
Linoleic acid | 14.1% (±2.6) | 14.3% (±2.5) | 0.477 |
Gamma-linolenic acid | 0.1% (±0.3) | 0.1% (±0.3) | 0.941 |
Dihomo-gamma-linolenic acid (DGLA) | 1.6% (±0.6) | 1.8% (±0.5) | 0.002 |
Arachidonic acid (AA) | 13.9%(±4.4) | 14.2%(±3.6) | 0.415 |
Docosapentaenoic acid (n-6) | 0.7% (±0.5) | 0.7% (±0.5) | 0.652 |
Total n-6 | 33.6% (±5.2) | 34.3% (±4.3) | 0.117 |
n-3, omega-3; n-6, omega-6; PHQ, Patient Health Questionnaire.
The 2-sample t-test was used to compare fatty acid levels between depressed and non-depressed patients.