Table 2.
Baseline clinical and neuropsychological characteristics of study participants
| Full responders (n =55) | Partial Responders (n =75) | Non Responders (n =45) | F or X2 | df1 | p | |
|---|---|---|---|---|---|---|
| Duration of Index Episode median2 (weeks) | 41 | 66 | 55 | 0.63 | 70 | 0.53 |
| Age of onset (years) | 60.9 (18.2) | 55.8 (21.2) | 54.3 (19.5) | 1.61 | 172 | 0.20 |
| %Recurrent (n) | 42% (23) | 43% (32) | 58% (26) | 3.23 | 2 | 0.20 |
| %Suicide ideation (HRSD item #3) | 4% (2) | 15% (11) | 12% (5) | 4.20 | 2 | 0.12 |
| Beck Hopelessness Score | 5.0 (4.5) | 8.2 (5.3) | 6.9 (5.1) | 6.33 | 169 | 0.002a |
| Mattis Dementia Rating Scale – scaled score | 8.5 (2.5) | 9.1 (2.9) | 8.9 (3.0) | 0.71 | 168 | 0.49 |
| Hamilton Rating Scale for Depression | 18.1 (2.8) | 18.5 (2.9) | 20.2 (3.6) | 6.72 | 172 | 0.002b |
| Hamilton Rating Scale for Anxiety | 16.7 (4.5) | 17.6 (4.2) | 20.6 (6.0) | 8.92 | 172 | 0.001b |
| Cumulative Illness Rating Scale total | 10.1 (3.8) | 10.5 (4.1) | 9.9 (3.9) | 0.32 | 172 | 0.73 |
| MOS – Physical component subscore | 44.9 (11.4) | 41.5 (10.9) | 37.8 (11.4) | 4.68 | 166 | 0.011c |
| MOS – Mental component subscore | 35.7 (10.6) | 32.0 (9.2) | 30.5 (8.3) | 3.86 | 166 | 0.023c |
| Interpersonal Support Evaluation List total | 35.4 (7.2) | 32.8 (7.9) | 30.7 (8.6) | 4.48 | 169 | 0.013c |
| Quality of Well Being total | 0.52 (0.12) | 0.50 (0.13) | 0.46 (0.11) | 2.85 | 168 | 0.061 |
1
Denominator degrees of freedom for F ratios, numerator df =2.
2
Natural log transformation prior to statistical comparison.
a
Tukey post-hoc: Full differ from partial responders.
b
Tukey post-hoc: Full and partial responders differ from non responders.
c
Tukey post-hoc: Full responders differ from non responders.