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. Author manuscript; available in PMC: 2013 Nov 5.
Published in final edited form as: Mol Pharm. 2012 Oct 19;9(11):3012–3022. doi: 10.1021/mp3004379

Table 3.

Comparison of growth inhibitory characteristics of various SCC23 loaded Ac-DEX nanoparticle formulations (X = no growth of bacteria, G = growth of bacteria).

SCC23 dose (μg/well) Ac-DEX-SCC23-1 Ac-DEX-SCC23-2 Ac-DEX-SCC23-3 Empty Ac-DEX Free SCC23
Pseudomonas aeruginosa (PA 01)
6.4 X X X G X
3.2 X X X G X
1.6 X X X G X
0.8 G X X G X
0.4 G G G G G
Pseudomonas aeruginosa (PA M57-15)
6.4 X X X G X
3.2 X X X G X
1.6 X X X G X
0.8 X X X G X
0.4 G G G G G
Methicillin-resistant Staphylococcus aureus (SA LL06)
6.4 X X X G X
3.2 X X X G X
1.6 X X X G X
0.8 X X X G X
0.4 G G G G X
Escherichia coli J53
6.4 X X X G X
3.2 X X X G X
1.6 X X X G X
0.8 G G G G G
0.4 G G G G G
Escherichia coli J53 + pMG101
6.4 X X X G X
3.2 X X X G X
1.6 G G G G X
0.8 G G G G G
0.4 G G G G G