Table1.

Heavy enzyme KIEs for alanine and [2-²H]-alanine (pH 8.9, 25 °C).

Substrate	${}_{}{}^{\mathrm{HE}}\mathrm{k}_{\mathrm{cat}}^{}$	${}_{}{}^{\mathrm{HE}}({\mathrm{k}}_{\mathrm{cat}}∕{\mathrm{K}}_{\mathrm{m}})$
L-ala	1.32 ± 0.04	1.3 ± 0.1
D-ala	1.21 ± 0.03	1.3 ± 0.1
[2-2H]-L-ala	1.67 ± 0.05	3.2 ± 0.4
[2-2H]-D-ala	1.40 ± 0.04	2.9 ± 0.4