Table 1. Patient characteristics.
| Characteristics | Proven/Probable CNS IA*(n = 8) | Possible/CNS IA*(n = 22) | No CNS IA (n = 25) | |
| Age (median, range) | 38 (4–82) | 42 (8–68) | 55 (0–73) | |
| Gender (female/male) | 4/4 | 11/11 | 14/11 | |
| Underlying disease | ||||
| AML | 1 | 8 | 3 | |
| ALL | 4 | 4 | 7 | |
| NHL | 2 | 4 | 10 | |
| AIHA | 0 | 0 | 1 | |
| MPN | 0 | 1 | 0 | |
| MDS | 0 | 1 | 0 | |
| Aplastic Anemia | 0 | 1 | 0 | |
| CVID | 0 | 1 | 0 | |
| Solid Tumor | 0 | 0 | 1 | |
| Other | 1 | 2 | 3 | |
| Among them patients after/with | ||||
| Allo-HSCT | 3 | 9 | 2 | |
| Auto-HSCT | 0 | 1 | 0 | |
| HIV infection | 0 | 1 | 0 | |
*
according to 2008 EORTC/MSG Criteria modified by Schwartz et al.
AML: acute myeloid leukemia; ALL acute lymphoblastic leukemia; NHL Non-Hodgkińs-Lymphoma; MDS: Myelodysplastic Syndrome; MPN: myeloproliferative neoplasia; Allo-HSCT: allogeneic hematopoietic stem cell transplantation; Auto-HSCT: autologous hematopoietic stem cell transplantation; AIHA: Autoimmunehemolytic anemia; CVID : common variable immunodeficiency syndrome; other: Primary chronic polyarthritis, HIV infection, sarcoidosis, miliary tuberculosis, bacterial meningitis.