Table 2. CBG gene (Serpina6) expression in the liver of male and female rats subjected to 30 d of cafeteria diet compared with controls.
form of expression of the data | male-control | male-cafeteria | female-control | female-cafeteria | p sex | p diet | p inter |
pmol mRNASerpina6/g tissue | 4.6±0.7 | 6.3±0.4 | 10.6±1.0 | 18.9±1.8 | <0.0001 | 0.0001 | 0.0034 |
pmol mRNASerpina6/whole liver | 54±8 | 88±10 | 88±7 | 167±20 | 0.0002 | 0.0002 | NS |
mRNASerpina6 transcripts per cell (×103) | 7.1±1.1 | 11.8±1.0 | 16.6±1.0 | 38.6±5.2 | <0.0001 | 0.0001 | 0.0051 |
The results are the mean ± sem of 6 animals per group. Statistical significance of the differences was established with a 2-way anova; inter = interaction between sex and diet.