Table 1. Hematological parameters in Lean and DIO WT and Gal-3 KO mice.
Lean WT | Lean Gal-3 KO | DIO WT | DIO Gal-3 KO | |
WBC (103/µl) | 9.47+/−0.48 | 9.79+/−1.11 | 10.72+/−0.68 | 12.18+/−0.98 |
# NE (103/µl) | 1.68+/−0.15 | 2.53+/−0.49 | 2.21+/−0.21 | 2.86/−0.29 |
# LY (103/µl) | 7.43+/−0.40 | 6.80+/−0.58 | 7.94+/−0.63 | 8.63+/−0.56 |
# MO(103/µl) | 0.28+/−0.03 | 0.40+/−0.12 | 0.28+/−0.04 | 0.31+/−0.06 |
# EO (103/µl) | 0.06+/−0.03 | 0.05+/−0.03 | 0.05+/−0.01 | 0.06+/−0.02 |
# BA (103/µl) | 0.02+/−0.01 | 0.02+/−0.01 | 0.01+/−0.00 | 0.01+/−0.00 |
%NE | 17.68+/−1.34 | 24.65+/−2.69* | 21.21+/−1.08 | 25.28+/−1.32* |
%LY | 78.49+/−1.61 | 71.21+/−3.19 | 75.50+/−1.46 | 71.77+/−1.51 |
%MO | 2.94+/−0.27 | 3.54+/−0.82 | 2.69+/−0.28 | 2.44+/−0.34 |
%EO | 0.69+/−0.32 | 0.47+/−0.29 | 0.49+/−0.11 | 0.45+/−0.15 |
%BA | 0.19+/−0.10 | 0.15+/−0.10 | 0.11+/−0.05 | 0.07+/−0.02 |
RBC (106/µl) | 9.25+/−0.10 | 9.59+/−0.19 | 10.01+/−0.25# | 10.42+/−0.21# |
Hb (g/dl) | 13.52+/−0.16 | 11.85+/−0.35* | 14.32+/−0.31 | 12.79+/−0.23* |
Hct | 44.83+/−0.45 | 36.24+/−0.93* | 47.86+/−1.35 | 41.20+/−0.59* |
MCV (fl) | 48.50+/−0.47 | 37.83+/−0.67* | 47.76+/−0.40 | 35.59+/−0.65* |
MCH (pg/cell) | 14.64+/−0.12 | 12.36+/−0.25* | 14.31+/−0.15 | 12.28+/−0.17* |
MCHC (g/dl) | 31.06+/−0.26 | 32.54+/−0.17 | 31.00+/−0.13 | 31.42+/−0.15 |
RDW (%) | 17.56+/−0.14 | 19.72+/−0.34* | 18.62+/−0.10 | 21.14+/−0.29* |
Plat (103/µl) | 895+/−65 | 1309+/−51* | 756+/−27 | 1009+/−50* |
MPV (fl) | 4.69+/−0.14 | 4.61+/−0.07 | 4.55+/−0.08 | 4.75+/−0.07 |
White blood cell (WBC) counts, Neutrophil (NE), Lymphocyte (LY), Monocyte (MO), Eosinophil (EO) and Basophil (BA) absolute numbers and percentages, Red Blood cell (RBC) numbers, Hemoglobin (Hb) levels, Hematocrit (Hct), Mean corpuscular volume (MCV), Mean corpuscular hemoglobin (MCH), Mean corpuscular hemoglobin concentration (MCHC), Red cell Distribution Width (RDW), platelet (Plat) number and Mean Platelet Volume (MPV) were evaluated on EDTA-anticoagulated peripheral blood using a Hemavet 950FS. Data are mean+/−SEM of 8–10 mice per group. *p<0.05 vs respective WT group; °p<0.05 vs respective Lean group.