A. A representative uterus from D7.5 WT mice. B. A representative uterus from D7.5 Prss35
(−/−) mice. A & B. Red arrows, implantation sites. C. The average number of implantation sites per mouse in the WT (+/+, N = 7) or Prss35
(−/−) (−/−, N = 7) females. All the mating males were Prss35
(−/−) for both groups except one WT male mated with one female in the WT group. Error bars, standard deviation. D∼I. Expression of decidualization markers in D7.5 uterus by in situ hybridization. D. Dtprp in WT uterus. E. Dtprp in Prss35
(−/−) uterus. F. Prlpi in WT uterus. G. Prlpi in Prss35
(−/−) uterus. H. Abp1 in WT uterus. I. Abp1 in Prss35
(−/−) uterus. Red star, embryo; M, mesometrial side; AM, antimesometrial side; scale bars, 500 µm.