Table 1. Relationship between expression of miR-195, Cyclin D1, and Bcl-2 and clinicopathologic factors in 81 TSCC patients.
miR-195 (T/N) | Cyclin D1(% ) | Bcl-2 (% ) | |||||||
Characteristics | No. | Mean ± SD | P | No. of low expression | No. of high expression | P | No. of low expression | No. of high expression | P |
Sex | 0.739 | 0.397 | 0.250 | ||||||
Male | 45 | 0.625±0.623 | 22 | 23 | 27 | 18 | |||
Female | 36 | 0.674±0.693 | 21 | 15 | 26 | 10 | |||
Age | 0.321 | 0.397 | 0.105 | ||||||
<60 y | 45 | 0.708±0.762 | 22 | 23 | 26 | 19 | |||
≥60 y | 36 | 0.570±0.502 | 21 | 15 | 27 | 9 | |||
Tumor size | 0.005 | 0.023 | 0.254 | ||||||
T1–T2 | 53 | 0.772±0.762 | 33 | 20 | 37 | 16 | |||
T3–T4 | 28 | 0.425±0.297 | 10 | 18 | 16 | 12 | |||
Differentiation | 0.747 | 0.932 | 0.608 | ||||||
Well | 35 | 0.709±0.753 | 18 | 17 | 23 | 12 | |||
Moderate | 38 | 0.592±0.590 | 21 | 17 | 26 | 12 | |||
Poor | 8 | 0.687±0.582 | 4 | 4 | 4 | 4 | |||
Clinical stage | 0.019 | 0.491 | 0.778 | ||||||
I–II | 48 | 0.780±0.770 | 27 | 21 | 32 | 16 | |||
III–IV | 33 | 0.466±0.394 | 16 | 17 | 21 | 12 | |||
Node metastasis | 0.493 | 0.056 | 0.488 | ||||||
Yes | 42 | 0.603±0.592 | 18 | 24 | 26 | 16 | |||
No | 39 | 0.705±0.728 | 25 | 14 | 27 | 12 | |||
Status | 0.010 | 0.254 | 0.088 | ||||||
Survival | 48 | 0.810±0.755 | 28 | 20 | 35 | 13 | |||
Death | 33 | 0.433±0.418 | 15 | 18 | 18 | 15 |
Abbreviations: T, tumor; N, nonmalignant tissue; T1–T4: T stage of TNM classification system.