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. 2013 Feb 22;8(2):e56634. doi: 10.1371/journal.pone.0056634

Table 1. Relationship between expression of miR-195, Cyclin D1, and Bcl-2 and clinicopathologic factors in 81 TSCC patients.

miR-195 (T/N) Cyclin D1(% ) Bcl-2 (% )
Characteristics No. Mean ± SD P No. of low expression No. of high expression P No. of low expression No. of high expression P
Sex 0.739 0.397 0.250
Male 45 0.625±0.623 22 23 27 18
Female 36 0.674±0.693 21 15 26 10
Age 0.321 0.397 0.105
<60 y 45 0.708±0.762 22 23 26 19
≥60 y 36 0.570±0.502 21 15 27 9
Tumor size 0.005 0.023 0.254
T1–T2 53 0.772±0.762 33 20 37 16
T3–T4 28 0.425±0.297 10 18 16 12
Differentiation 0.747 0.932 0.608
Well 35 0.709±0.753 18 17 23 12
Moderate 38 0.592±0.590 21 17 26 12
Poor 8 0.687±0.582 4 4 4 4
Clinical stage 0.019 0.491 0.778
I–II 48 0.780±0.770 27 21 32 16
III–IV 33 0.466±0.394 16 17 21 12
Node metastasis 0.493 0.056 0.488
Yes 42 0.603±0.592 18 24 26 16
No 39 0.705±0.728 25 14 27 12
Status 0.010 0.254 0.088
Survival 48 0.810±0.755 28 20 35 13
Death 33 0.433±0.418 15 18 18 15

Abbreviations: T, tumor; N, nonmalignant tissue; T1–T4: T stage of TNM classification system.