Table 4. Expression scores of CTSE, MUC5AC, and MUC2 (from 1 to 4 respectively) in gastric tumors cells (cancer or adenoma) and adjacent normal cells (non-tumorous epithelial cells of background mucosa).

Histology ofgastric tumors	CTSE intumor cells	CTSE in adjacentnormal cells	MUC5AC intumor cells	MUC5AC inadjacent normalcells	MUC2 intumor cells	MUC2 in adjacentnormal cells
Sig	3.57±0.43	3.86±0.14	3.57±0.43	3.29±0.18	1.43±0.43	1.43±0.30
Adenoma	1.33±0.21	3.17±0.31	1.67±0.42	3.67±0.21	1.83±0.31	3.17±0.31
Tub1	1.65±0.12	3.04±0.11	1.88±0.15	2.92±0.10	1.54±0.10	2.94±0.11
Tub2	2.33±0.26	2.17±0.11	2.08±0.31	2.75±0.25	1.42±0.19	2.58±0.29
Pap	2.14±0.26	2.57±0.20	3.14±0.40	2.86±0.14	1.86±0.26	3.29±0.42
Total	1.93±0.11	2.95±0.09	2.14±0.13	2.98±0.08	1.56±0.08	2.81±0.10

NOTE: Histology of gastric tumors was evaluated according to the 3rd edition of Japanese Classification of Gastric Carcinoma. Staining of CTSE, MUC5AC, and MUC2 in cells in each gastric tumor was evaluated compared with CTSE-deficient colorectal epithelium, MUC5AC-deficient colorectal epithelium, and MCU2-deficient normal gastric epithelium respectively. Values assigned to CTSE, MUC5AC, and MUC2 staining (from 1 to 4) were decided as follows: 1, percentage of cells with positive staining ranges from 0% to 10%; 2, percentage of cancer cells with positive staining ranges from 10% to 50%; 3, percentage of cancer cells with positive staining ranges from 50% to 90%; 4, percentage of cancer cells with positive staining is greater than 90%.