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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Radiat Res. 2012 Nov 30;179(1):9–20. doi: 10.1667/RR3089.1

TABLE 3.

Parameters for Chromosome Exchange and Breakpoint Doses Response Fits

Damage parameter Cell, radiation Model* α (D) β (D2) c (Intercept)
Simple exchanges Fibroblasts γ rays α/β 0.20 ± 0.05 0.03 ± 0.01 0.03 ± 0.04
Lymphocytes γ rays α/β 0.27 ± 0.10 0.04 ± 0.02 −0.004 ± 0.080
Fibroblasts α particles Linear 2.02 ± 0.16 0.07 ± 0.04
Lymphocytes Fe ions Linear 0.53 ± 0.02 0.02 ± 0.02
Complex exchanges Fibroblasts γ rays Quadratic 0.012 ± 0.001 0.002 ± 0.005
Lymphocytes γ rays Quadratic 0.037 ± 0.002 −0.007 ± 0.001
Fibroblasts α particles Linear 0.75 ± 0.09 0.009 ± 0.021
Lymphocytes Fe ions Linear 0.40 ± 0.02 −0.01 ± 0.02
Complex chromosome breakpoints Fibroblasts γ rays Quadratic 0.038 ± 0.003 0.01 ± 0.02
Lymphocytes γ rays Quadratic 0.17 ± 0.01 −0.07 ± 0.09
Fibroblasts α particles Linear 2.70 ± 0.32 0.015 ± 0.074
Lymphocytes Fe ions α/β 0.53 ± 0.31 1.16 ± 0.20 0.10 ± 0.09
*

By standard practice, we have fit the γ-ray data to linear-quadratic (α/β) models even though such models failed to provide a significantly better fit to the data than simple linear ones. The γ-ray responses for complex exchange breakpoints, however, were fit by pure quadratic models since linear-quadratic fits returned negative α coefficients.