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. Author manuscript; available in PMC: 2013 Feb 24.
Published in final edited form as: Lancet. 2011 Jun 27;378(9788):319–327. doi: 10.1016/S0140-6736(11)60895-7

Figure 4.

Figure 4

(A): The ratio (GAD-alum ×3 to alum ×3) of treatment effect on 1 year stimulated C-peptide AUC mean within categories of pre-specified baseline factors. The estimates are from the analysis of covariance modeling log of C-peptide adjusting for age, gender, baseline value of C-peptide, the indicated categorized factor, treatment assignment, and treatment interaction terms. The homogeneity test of treatment effect was significant for DR3 allele status (p = 0.04). (B): The ratio (GAD-alum ×2 to alum ×3) of treatment effect on 1 year stimulated C-peptide AUC mean within categories of pre-specified baseline factors. The estimates are from the analysis of covariance modeling log of C-peptide adjusting for age, gender, baseline value of C-peptide, the indicated categorized factor, treatment assignment, and treatment interaction terms.